Research Summary: Ageing causes a decline in the function of human skin, while factors such as medical conditions, drugs, and environmental irritants add to the compromised skin and predispose it to certain conditions. Superimposed on the changes of physiological ageing are changes characterized by chronic sun exposure. Skin neoplasia, whether benign, premalignant, or malignant, is more common in the elderly. It is important to identify benign conditions, as it is crucial that lesions with malignant potential be recognized so that timely treatment can prevent serious malignancies. Ultraviolet radiation is the major etiologic factor for the development of skin cancer.Pruritic conditions...
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Research Summary: Omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) are nowadays desirable components of oils with special dietary and functional properties. Their therapeutic and health-promoting effects have already been established in various chronic inflammatory and autoimmune diseases through various mechanisms, including modifications in cell membrane lipid composition, gene expression, cellular metabolism, and signal transduction.The application of ω-3 and ω-6 PUFAs in the most common skin diseases has been examined in numerous studies, but their results and conclusions were mostly opposing and inconclusive. It seems that combined ω-6, gamma-linolenic acid (GLA), and ω-3 long-chain PUFAs supplementation exhibits the highest...
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Research Summary:Omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) are desirable components of oils with special dietary and functional properties. Their therapeutic and health-promoting effects have already been established in various chronic inflammatory and autoimmune diseases through mechanisms such as modifications in cell membrane lipid composition, gene expression, cellular metabolism, and signal transduction. The application of ω-3 and ω-6 PUFAs in common skin diseases has been examined in numerous studies, but the results and conclusions were often opposing and inconclusive. It seems that a combination of ω-6, gamma-linolenic acid (GLA), and ω-3 long-chain PUFAs supplementation exhibits the highest potential...
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Research Summary: Proteins are fundamental to cell structure and function. They provide the necessary framework that gives cells their shape and are involved in nearly every task within a cell, from metabolism to DNA replication.Nucleic acids, such as DNA and RNA, store and convey the genetic instructions for the production of proteins. These molecules ensure that proteins are synthesized in the appropriate quantity, at the correct time, and within the right cellular location.Phospholipids form the basic structure of cell membranes. These lipid molecules arrange themselves in a bilayer, creating a barrier that regulates what enters and exits the cell, maintaining...
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