Research — Ingredients

Plant-Derived Antioxidants: Significance in Skin Health and the Ageing Process

Plant-Derived Antioxidants: Significance in Skin Health and the Ageing Process

Research Summary:  Natural substances have traditionally been used in skin care for centuries. There is now an ongoing search for new natural bioactives that not only promote skin health but also protect the skin against various harmful factors, including ultraviolet radiation and free radicals. Free radicals, by disrupting defense and restoration mechanisms, significantly contribute to skin damage and accelerate aging. Natural compounds present in plants exhibit antioxidant properties and the ability to scavenge free radicals. The increased interest in plant chemistry is linked to the growing demand for plant materials as natural antioxidants. This review focuses on aromatic and medicinal...

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Niacinamide: A Topical Vitamin with Wide-Ranging Skin Appearance Benefits

Niacinamide: A Topical Vitamin with Wide-Ranging Skin Appearance Benefits

Research Summary: Niacinamide is vitamin B3, an essential nutrient. In the body, it is converted to the co-factors NADH and NADPH, which are involved in many biochemical reactions. Dietary deficiency of this water-soluble member of the vitamin B family causes pellagra, a disease that includes dermatitis and red lesions. Pellagra caused thousands of deaths in the United States in the first half of the twentieth century, until simple dietary supplementation with this absorbable vitamin was found to cure the disorder.NAD+ and NADPH levels in skin cells decline with age. Thus, supplementing skin with the precursor to these vital co-factors has...

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A Review of Clinical Efficacy of Topical Vitamin C and Its Derivatives

A Review of Clinical Efficacy of Topical Vitamin C and Its Derivatives

Research Summary: The last two decades have seen an increase in active-led skin care products in over-the-counter and retail marketplaces. Consumers have become more knowledgeable about the ingredients used in topical products, resulting in formulations with vitamins and other active ingredients gaining popularity. Further, with the need for instantaneous and short-term benefits, consumers are moving towards high doses of active products. This poses a challenge for formulation scientists to stabilize high active doses and ensure potency over the shelf life. Vitamin C, or ascorbic acid, is one such ubiquitous active commonly found in topical products claiming brightening, skin firming, and...

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PHYTOCHEMICAL REVIEW OF ALOE VERA WITH EMPHASIS ON ITS COSMETIC  APPLICABILITY

PHYTOCHEMICAL REVIEW OF ALOE VERA WITH EMPHASIS ON ITS COSMETIC APPLICABILITY

Research Summary: Introduction: Ever since the inception of man’s perception towards beauty, there has been a constant inclination toward the care of one’s appearance. The concept of beauty in Ayurveda is present as early as in *Caraka Samhitā* in the form of *varnya dashemani*. Beauty presents a standard of comparison, and it can cause resentment and dissatisfaction when not achieved. For the maintenance of beauty, there has been a dedicated branch of science—cosmetics. However, owing to side effects like allergies, photosensitivity, and even malignancies due to synthetic chemicals, there has been a growing demand for plant-based cosmetics. Aloe vera is...

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