Verified 5-star reviews

Advanced formulas, working in harmony.

Over-cleansing and complicated routines aren’t just harsh—they accelerate aging.

Many people unknowingly strip away their skin’s natural barrier, leading to irritation, dryness, and flare-ups of sensitivity. But it doesn’t stop there.

90% of skin aging comes from our daily habits and environmental exposure.

Everyday UV and blue light, pollution, and stress silently contribute to how fast we age. Modern challenges demand MDRN solutions.

Your skin doesn’t need more complexity—it needs balance.

The good news? The future of skincare is about harmony: fewer products, and efficient formulas, engineered with precision.

Why choose HyPrEn?

Designed to boost hydration, protection, and skin enrichment. This is a complete dermal health and anti-aging system delivered through 4 essential products

Experience advanced ingredients in the right amount at the right frequency. Includes hyaluronic acid, vitamin C, E, B3 and a range of antioxidants to support and respect your skin's natural processes.

A streamlined system that goes beyond the modern standards of skincare.

Our testing and trials have incredible results. Join the 90% of users who saw noticeable skin improvements in just 72 hours.

Try HyPrEn today and start your journey to healthier, happier skin.

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  • Supports true skin health
  • Vitamins & mineral replacement
  • Protects from UV and pollution
  • Rebalance oils & absorb toxins
  • Repairs damage from over cleansing
  • Supported by 200+ research studies
MDRN

What's included in the System?

Includes:

1x Hydrating Créme with SPF.
2x jars of Anti-Aging Hydrogel Eyepatches.
8x Gladiator Hydrating Face Masks.
1x Amazonian or Volcanic Infused Clay.

MDRN

60 days of hydration, protection and enrichment.

Fundamentals for healthier, younger skin.
Created with board-certified dermatologists with precision and minimalism in mind.

The Elements

Skincare technology has made huge advancements in the last decade.
We combine cutting-edge formulations with decades of research.
Four multifunctional products for an advanced streamlined routine.

Hydrating Face Mask

The gold standard in facemask ergonomics, our most advanced, cooling and enriching formula. For long lasting weekly enrichment. 

The Most Advanced Hydration

  • Vitamin C to stimulate collagen production
  • Hyaluronic Acid to retain moisture for days
  • Grape Extract acts as an antioxidant shielding pollution
  • Aloe Vera soothes and calms skin

The best thing i've ever put on my skin.

"Just like a spa treatment at home. Result is 10/10."

Hydrating Creme with SPF

Hydrating creme with anti-ageing UV protection. Enriching, non greasy texture optimised for sport. 

Hydrate + Protect

  • Hyaluronic Acid to retain 1000x its weight in water.
  • SPF15 for daily broad spectrum UV shield.
  • Niacinamide to ease inflammation from conditions like acne and eczema.
  • Ocean compound (seaweed) for anti-aging rich in vitamins & minerals

Fantastic

"My go to daily moisturiser, versatile and non greasy"

Hydrogel Eye Patches

A daily anti-aging treatment engineered for fine lines and wrinkles. Cool and soothe tired looking eyes. 

Daily Anti-aging

  • Hydrolyzed collagen boost which declines with age. 
  • Cooling aloe vera for sharper morning eyes.
  • Hylauronic acid to retain 1000x its weight in water.
  • Trehalose to protect from damage by UV exposure and pollution.

HyPrEn has been a game-changer

"Even with sleepless nights caused by my toddler, using the patches in the morning helps me feel refreshed and ready for the day."

Volcanic & Amazonian Clay

Nutrient dense clays cleanse the traditional way whilst remineralising your skin. This method supports true skin health and oil balance and avoids overcleansing.

Cleanse & Enrich a better way

  • Advanced clays that deeply cleanse, enrich and remineralise skin.
  • Volcanic or Amazonian clay options for oily or sensitive skin types.
  • Nutrient dense with potassium, magnesium and antioxidants
  • Ancient skincare method that avoids skin damage whilst detoxifying.

Less is definitely more. 

“Undeniable improvements from the very first cleanse. Gives me a softer, brighter complexion I haven't had in years.”

Get true skin health with HyPrEn**

  • HyPrEn Skincare System 60 days of complete skincare treatments, ships every 60 days radiance or refund
  • Hydrating Gladiator Masks x8 Weekly advanced enrichment and hydration £39.20Included
  • Hydrating Crème with SPF Daily hydration and UV protection £24.00Included
  • Hydrogel Eye Patch Jar x2 30 pairs per jar for daily hydration. £45.00Included
  • with Amazonian ClaySoothing cleanse to enrich those with more sensitive skin. with Volcanic Clay Detoxifying cleanse to enrich and rebalance oilier skin. £21.90Included
  • Total £130£82.00
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Rethinking skincare for true skin health

At MDRN we're grounded in research to achieve true skin health.

3 Pillars of Skin Health: Hydrate, Protect, Enrich

Environmental and lifestyle stressors, aging and common skin conditions impact us all. HyPrEn addresses these with daily and weekly products supporting three pillars: Hydrate, Protect, and Enrich.

  • Hydrate: Keeping skin glowing supple with daily hydration and weekly treatments.
  • Protect: Defend against pollution and UV damage with antioxidants and a mineral-based UV shield.
  • Enrich: Boost skin structure and elasticity by focusing on vitamins and mineral support.

Progressive Product Development 

HyPrEn disrupts traditional skincare with ethical practices, clean beauty, and real results, adhering to ISO 22716 and GMP standards.

  • Ethically-Sourced: 100% vegan, cruelty-free, and sustainably sourced ingredients.
  • Clean Development: Free from parabens, gluten, and toxic chemicals, ensuring gentle yet effective skincare.
  • Radiance or Refund Promise: If no improvement in radiance within 30 days, get a full refund.

Science-Backed Innovation

MDRN, driven by research from top dermatologists and scientists, supports HyPrEn with over 200 studies ensuring safety, efficacy, and performance.

  • Expert Team: Leading dermatologists and cellular biologists formulate advanced, effective products.
  • Research-Led Formulations: Balanced ingredients for optimal skin health, natural rejuvenation and repair.

Disrupting Industry Practices

HyPrEn challenges industry norms, focusing on research and best practices rather than trends.

  • Against Overconsumption: Reduce damage from over-cleansing and dependency on products.
  • Affordable Quality: Making advanced skincare accessible to more people.
  • Full Transparency: Educating on ingredient effectiveness and impact on skin microbiology.

Full Ingredients list

Hydrating Face Mask: Water / Aqua / Eau, Glycerin, Propylene Glycol, Betaine, Trehalose, Butylene Glycol, Hydroxyacetophenone, 1,2-hexanediol, Pentylene Glycol, Carbomer, Aloe Barbadensis (Aloe Vera) Leaf Extract, 3-o-ethyl Ascorbic Acid, Sodium Hyaluronate, Hydroxyphenyl Propamidobenzoic Acid, Bergenia Crassifolia Root Extract, Punica Granatum (Grape) Extract, Phenoxyethanol, Hylhexylglycerin, Fragrance / Parfum.

Hydrating Cream with SPF: Aqua, Glycerin, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Propylene Glycol, Ethylhexyl Methoxycinnamate, Dimethicone, Cyclopentasiloxane, Cetearyl Alcohol, Titanium Dioxide, Steareth-21, Steareth-2, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, Potassium Cetyl Phosphate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Stearate, Hydroxyacetophenone, 1,2-Hexanediol, Niacinamide, PEG-50 Hydrogenated Castor Oil, Isohexadecane, Phenoxyethanol, Bisabolol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Laminaria Digitata Extract, Cyclohexasiloxane, Polysorbate 80, Dipropylene Glycol, Cetyl Phosphate, Panthenol, Xanthan Gum, Parfum, Aluminum Hydroxide, Silica, Alumina, Sodium Hyaluronate, Sorbitan Oleate, Disodium EDTA, Hydroxyethylcellulose, Polyglyceryl-10 Laurate, Decyl Glucoside

Hydrogel Eye Patches: Aqua, glycerin, propylene glycol, chondrus crispus powder, trehalose, betaine, glucomannan, hydrolyzed collagen,1,2-hexanediol, hydroxyacetophenone, potassium chloride, hydroxyethylcellulose, butylene glycol, pentylene glycol, aloe barbadensis leaf extract, tocopherol, sodium hyaluronate, ci42090, hydroxyphenyl propamidobenzoic acid, parfum.

Volcanic Clay: Aqua, montmorillonite, kaolin, glycerin, ethylhexyl palmitate, butylene glycol, peg-100 stearate, charcoal powder, titanium dioxide, glyceryl stearate, phenoxyethanol,peg-40 hydrogenated castor oil, macadamia ternifolia seed oil, hydroxyethylcellulose, peg-50 hydrogenated castor oil, propylene glycol, bisabolol, menthyl lactate, hydroxyacetophenone,1,2-hexanediol, ethylhexylglycerin, vanillyl butyl ether, parfum, Bergenia crassifolia root extract, hamamelis virginiana (witch hazel) extract, rubus chingii extract.

Amazonian Clay: Aqua, montmorillonite, kaolin, glycerin, ethylhexyl palmitate, butylene glycol, amazonian clay. Peg-100 stearate, titanium dioxide, glycerylstearate, phenoxyethanol, peg-40 hydrogenated castor oil. Macadamia ternifolia seed oil, hydroxyethyl cellulose, peg-50 hydrogenated castor oil, propylene glycol, bisabolol, menthyl lactate, hydroxyacetophenone,1,2-hexanediol,ethylhexylglycerin, vanillyl butyl ether, parfum, bergenia crassifolia root extract, hamamelis virginiana extract,rubus chingii extract.

89 Advanced ingredients

215 Supporting scientific papers and counting

Radiance or Refund.

30-Day Money Back Guarantee

If you don’t observe a significant improvement in your skin’s radiance within 30 days of using our products, we will provide a full refund, no questions asked.

Our commitment includes:

  • Risk-Free Trial: Experience the full potential of HyPrEn with no financial risk.
  • Proven Results: Our products are developed with the latest advancements in skincare science.
  • Customer-Centric Approach: If you are not completely satisfied with the results, we are committed to making it right.

Backed by 200+ studies.

We conducted a comprehensive trial with 125 people. Participants reported seeing significant improvements in skin health, radiance, and a positive impact on a range of skin concerns.

AT 5 DAYS*

96% of participants felt fast improvement in skin texture.

100% of participants felt HyPrEn was a better and more enjoyable skin routine.

AT 30 DAYS*

93% of participants had reduced skin problems and softer, smoother skin.

89% of participants said the quality and quantity of products exceeded expectations.

Buy HyPrEn

Aging is inevitable, but looking older isn't.

Hydrated and enriched skin has the ability to repair itself and stay healthier for longer.

Skin conditions, pollution and daily UV & blue light exposure accelerate damage and aging. HyPrEn is a solution designed to boost hyaluronic acid, elastin and collagen to ensure younger looking skin.

AT 5 DAYS*

10% of ageing is down to your DNA and genetics.

90% of ageing is down to extrinsic factors like your habits, lifestyle, environment and skin care routines.

The right ingredients, the right quantity, at the right time.

  • Man wearing a gold foil hydration sheet mask by MDRN.

    Enrich and hydrate once a week.

  • Moisturise and protect daily.

  • Hydrate and enrich daily.

  • Cleanse and remineralise weekly.

What our experts have to say

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FAQs

Is HyPrEn a good match for my skin?

Our HyPrEN system is suitable for a variety of skin types, including dry, oily, combination, and sensitive skin. If you are looking for a comprehensive skincare system that offers hydration, protection, and enrichment, HyPrEn is an excellent choice. The system is designed to address common skincare concerns such as dryness, fine lines, dullness, and exposure to environmental stressors.

How fast does it work?

You'll begin to notice some immediate benefits, such as increased hydration and a more radiant complexion after the first few uses. For the full impact on the microbiome and enhanced skin texture, it typically takes about 4-6 weeks of consistent use. Individual results may vary also depending on your diet and lifestyle.

What are the benefits can I expect from HyPrEn?

By incorporating HyPrEN into your skincare routine, you can expect several benefits:

  • Hydration and Moisture Retention: Deeply hydrates the skin and locks in moisture.
  • Antioxidant Protection: Protects against pollution and blue light exposure (screens and phones).
  • Anti-Aging Effects: Reduces fine lines and wrinkles, tightens the skin, and improves overall texture.
  • Soothed and Rejuvenated Skin: Soothes irritation and puffiness, especially around the eyes.
  • Detoxification: Cleanses and detoxifies the skin, drawing out toxins and impurities.
  • Improved Skin Health: Enhances skin health through enriched formulas with vitamins and minerals.

Which clay should I choose?

Choose Volcanic Clay if you have oily skin, live in a polluted area, or need detoxifying benefits. It deep cleanses, controls oil, and offers some antioxidant protection.

Opt for Amazonian Clay if your skin is dull, prone to redness, or in need of stronger antioxidant protection. It soothes, brightens, and nourishes the complexion.

Are HyPrEN products researched and tested?

All our products are formulated with high-quality ingredients and each product undergoes rigorous testing to ensure it meets our standards for performance and skin compatibility. Additionally, our custom formulas prioritise ingredients that are backed by 200 scientific studies and supported by leading dermatologists.

For more information and reports head over to our R&D section.

**True skin health relies on a balanced microbiome and optimal pH levels, supporting the skin's natural barrier and defense mechanisms. A diverse microbiome protects against pathogens and reduces inflammation, while a slightly acidic pH (4.5-5.5) is vital for enzyme function and barrier integrity. Key ingredients in HyPrEn like hyaluronic acid, antioxidants, and vitamin C ensure hydration, repair, and protection. Proper formulation with balanced concentrations of active ingredients prevents many skin issues and maintains optimal skin health.

MADE-ST LTD Company number 12971202: 30 Westgate, Leeds, LS21 3AS.