Research

Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications

Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications

Research Summary The skin is the largest organ of the body and serves a wide range of functions. Within the skin's compartments, including the epidermis and hair follicles, reside stem cells that are essential for skin homeostasis and regeneration. These stem cells also play a key role in wound repair, helping restore the integrity and function of damaged tissue. However, when the wound healing process is unsuccessful, it can result in non-healing wounds. Chronic wounds, in particular, are often the result of stem cell depletion, along with a variety of other cellular and molecular mechanisms, many of which remain poorly...

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Skin Care Formulations and Lipid Carriers as Skin Moisturizing Agents

Skin Care Formulations and Lipid Carriers as Skin Moisturizing Agents

Research Summary Skin care formulations have evolved as the interaction of health and beauty products for the skin. Their benefits are based on the combination of cosmetic active ingredients and targeted ap-plication. Cosmetic actives have been used in novel formulations for decades (sunscreens, anti-agingtreatments, etc.), but the problems with their low solubility, low penetration, and physicochemicalinstability when applied to the skin have yet to be solved. One way to circumvent these shortcomingsis to use lipid carriers, which are known to play an important role in the solubility of poorly solublecompounds by facilitating skin permeation and improving stability. This review addresses...

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Evaluating UVB and UVA Boosting Technologies for Chemical and Physical Sunscreens

Evaluating UVB and UVA Boosting Technologies for Chemical and Physical Sunscreens

Research Summary There are currently 14 organic and 2 inorganic UV filters approved in the United States. Due to coral reef safety concerns, octinoxate and oxybenzone have been banned in Hawaii, Key West, FL, and the US Virgin Islands. Additionally, octocrylene is being studied for its potential impact on coral reef safety, leaving 11 organic UV filters as viable options for sunscreen manufacturers, though there are limitations on their combination. Since consumers are always seeking sunscreens with high SPF and broad-spectrum protection, the need for UVB and UVA protection-boosting technologies is greater than ever.In a preliminary study, about two dozen...

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Base metal iron catalyzed sustainable oxidation of vanillyl alcohol to vanillic acid in deep eutectic solvents and implementation of vanillic acid for fine-chemical synthesist

Base metal iron catalyzed sustainable oxidation of vanillyl alcohol to vanillic acid in deep eutectic solvents and implementation of vanillic acid for fine-chemical synthesist

Research Summary In the modern era, sustainable development for the production of fine chemicals from abundant biomass using various chemical transformations has become a significant trend in scientific research. This approach offers a sustainable alternative to petrochemicals as the primary source of fine chemicals. Lignin, in particular, is an alternative major source of monomeric phenolic compounds, and the oxidation of lignin-based monomeric phenolics for the synthesis of fine chemicals is gaining serious attention. For instance, biomass-derived vanillin or vanillyl alcohol can be oxidized to vanillic acid, which serves as a new building block for the synthesis of various value-added products.In...

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