Research

Research Summary Various methods of evaluating a humectant’s moisture retention have unique mechanisms. Hence, for designing advanced or efficient ingredients in cosmetic products, a clear understanding of the differences among these methods is required. The aim of this study was to analyze the moisture-retention capacity of glycerin, a common ingredient in cosmetic products. Specifically, this study applied gravimetric analysis, transepidermal water loss (TEWL) analysis, and differential scanning calorimetry (DSC) to examine the evaporation of glycerin solutions of different concentrations. The results revealed that the moisture-retention capacity of glycerin increased with glycerin concentration from 0 to 60 wt%. Notably, glycerin at...

Research Summary Various methods of evaluating a humectant’s moisture retention have unique mechanisms. Hence, for designing advanced or efficient ingredients in cosmetic products, a clear understanding of the differences among these methods is required. The aim of this study was to analyze the moisture-retention capacity of glycerin, a common ingredient in cosmetic products. Specifically, this study applied gravimetric analysis, transepidermal water loss (TEWL) analysis, and differential scanning calorimetry (DSC) to examine the evaporation of glycerin solutions of different concentrations. The results revealed that the moisture-retention capacity of glycerin increased with glycerin concentration from 0 to 60 wt%. Notably, glycerin at...

Research Summary Several compounds are commonly used as flavors in foods such as chewing gum and candy to generate a pleasant cool sensation, which can have a soothing effect on the upper respiratory tract. Menthol and eucalyptol are the flavors most widely used as cooling agents, and their effect is supported by scientific data. The cool sensory perception they induce is due to their ability to activate cold receptors, particularly the transient receptor potential cation channel subfamily M member 8 (TRPM8), found in the skin and oral cavity. The ability to activate cold receptors has also been shown for non-volatile...

Research Summary Moisturizing creams are useful treatment adjuncts in inflammatory dermatoses and have beneficial effects in treating dry, scaly skin. A study was conducted to compare the effects of dryness and skin permeability using a new moisturizing cream with 20% glycerine against its placebo and a medically authorized cream containing 4% urea (combined with 4% sodium chloride) in the treatment of dry skin.Methods: The study involved 109 patients with atopic dermatitis who were treated for 30 days with a moisturizer in a randomized, parallel, and double-blind fashion. Transepidermal water loss (TEWL) and skin capacitance were measured instrumentally, and a dermatologist...