Research

Research Summary Cosmetics are pharmaceutical products used for improving skin appearance and body odor. These products are available in various forms, ranging from lotions, creams, powders, and more. Cosmetics are used for cleansing, protecting, and moisturizing the skin. Generally, consumers prefer cosmetics that have less harmful effects on their skin. "Cosmeceutical" products have now been developed by many pharmaceutical industries. According to Duroja et al., a cosmeceutical is the combination of a topical cosmetic and a pharmaceutical that is used for enhancing beauty through ingredients that have biological functions related to the skin [1]. The topical cosmetic, which contains antioxidants,...

Research Summary In recent years, interest in the health effects of natural antioxidants has increased due to their safety and applicability in cosmetic formulation. Nevertheless, the efficacy of natural antioxidants in vivo is less documented than their prooxidant properties in vivo. Plant extracts rich in vitamins, flavonoids, and phenolic compounds can induce oxidative damage by reacting with various biomolecules while also providing antioxidant properties. Because the biological activities of natural antioxidants differ, their effectiveness for slowing the aging process remains unclear. This review article focuses on the use of natural antioxidants in skincare, the possible mechanisms underlying their desired effect,...

Research Summary In recent years, interest in the health effects of natural antioxidants has increased due to their safety and applicability in cosmetic formulation. Nevertheless, the efficacy of natural antioxidants in vivo is less documented than their prooxidant properties in vivo. Plant extracts rich in vitamins, flavonoids, and phenolic compounds can induce oxidative damage by reacting with various biomolecules while also providing antioxidant properties. Because the biological activities of natural antioxidants differ, their effectiveness for slowing the aging process remains unclear. This review article focuses on the use of natural antioxidants in skincare, the possible mechanisms underlying their desired effect,...

Research Summary Chronic cutaneous wounds represent a major issue in medical care and are often prone to infections. Purpose: The aim of this study was the design of a clay mineral-drug nanocomposite based on montmorillonite and norfloxacin (NF, antimicrobial drug) as a powder for cutaneous application, to enhance wound healing in infected skin lesions. Methods: The nanocomposite has been prepared by means of an intercalation solution procedure. Adsorption isotherm, solid-state characterization of the nanocomposite, drug loading capacity, and its release have been performed. Moreover, cytocompatibility, in vitro fibroblast proliferation, and antimicrobial activity against Pseudomonas aeruginosa and Staphylococcus aureus were assessed....