Research — aging

Research Summary:Background: Vitamin C is a micronutrient present in high concentrations in normal skin and is a highly prescribed cosmeceutical known for its protective effects against ultraviolet-induced pigmentation and its role in regulating collagen production. However, there is a lack of studies evaluating the efficacy of topical vitamin C in photoaging and melasma, making this systematic review the first to assess the existing evidence.Aim: This systematic review aims to evaluate whether topical vitamin C could be effective in reversing signs of photoaging and treating melasma.Methods: Prospective, randomized controlled trials that assessed protocols involving topically applied vitamin C in patients with...

Research Summary: The aging population and a desire to maintain a youthful appearance have propelled the recent surge in the U.S. cosmeceuticals market. The rapidly growing number of products claiming to diminish fine lines and wrinkles, decrease redness, smooth texture, and fade discoloration has led to much confusion and misinformation among dermatologists and consumers alike.Cosmeceuticals can be a useful adjunct to prescription medications and office procedures. Therefore, it is important for dermatologists to understand the science behind these products to better educate themselves and their patients.We present an update on the following categories of cosmeceuticals: antioxidants, growth factors, peptides, anti-inflammatories/botanicals,...

The interactions between the sun and the skin have both beneficial and harmful aspects. While the sun provides important positive effects, there are also serious harmful consequences to consider, particularly from ultraviolet radiation, commonly referred to as UV-A and UV-B. To mitigate these harmful effects, the topical application of sunscreens and the avoidance of extreme sun exposure are widely recognized as the most effective strategies to prevent sunburn and skin edema. Additionally, this approach can efficiently reduce the risk of developing skin cancer.The primary aim of sunscreen products is to minimize the damage caused by sun exposure while maintaining good...

Research Summary: It is estimated that total sun exposure occurs non-intentionally in three quarters of our lifetimes. Our skin is exposed to the majority of UV radiation during outdoor activities, such as walking, practicing sports, running, hiking, etc., and not when we are intentionally exposed to the sun on the beach. We rarely use sunscreens during those activities, or at least not as much and as regularly as we should, making us commonly prone to acute and chronic sun damage of the skin. The only protection of our skin is endogenous (synthesis of melanin and enzymatic antioxidants) and exogenous (antioxidants,...