nouvelles-1 — Ingredients

Research Summary: Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to be less immunogenic, or perhaps even non-immunogenic, with a variety of physicochemical properties, there is mounting evidence that PEG causes immunogenic responses when conjugated with other materials such as proteins and nanocarriers. Under these conditions, PEG with other materials can result in the production of anti-PEG antibodies after administration.The antibodies that are induced seem to have a deleterious impact on the therapeutic efficacy of subsequently administered PEGylated...

Research Summary: In recent years, interest in the health effects of natural antioxidants has increased due to their safety and applicability in cosmetic formulations. Nevertheless, the efficacy of natural antioxidants in vivo is less documented than their prooxidant properties in vivo. Plant extracts rich in vitamins, flavonoids, and phenolic compounds can induce oxidative damage by reacting with various biomolecules while also providing antioxidant properties.Because the biological activities of natural antioxidants differ, their effectiveness in slowing the aging process remains unclear. This review article focuses on the use of natural antioxidants in skincare and the possible mechanisms underlying their desired effects,...

Research Summary: World consumers are looking for personal care products that supply multiple benefits with minimal effort. They also expect the latest technological advances to be incorporated into innovative formulations. The trend toward therapeutic cosmetics will lead to a better understanding of modern ingredients and their assessment techniques. To obtain skin care formulations with real consumer-perceivable benefits and to optimize sensory attributes, formulators are resorting to technology that until recently was exclusively used in cosmetic products. Various formulations come under special delivery systems like Vesicular, Particulate systems, and emulsions type, along with their applications, as shown in this article. This...

Research Summary: To review the composition, actions, and clinical applications of the *Aloe vera* plant in dentistry and to establish its effectiveness as an invaluable adjunct in the treatment of dental diseases.Method. A manual and electronic literature (MEDLINE, Cochrane Central Register of Controlled Trials, and Google Scholar) search was performed up to July 2013 for in vitro and in vivo studies and research presenting clinical, microbiological, immunological, and patient-centered data to validate the efficacy of Aloe vera gel in dentistry. A total of 38 titles, abstracts, and full-text studies were selected and reviewed.Aloe vera has various medicinal properties such as...