nouvelles-1 — Ingredients

Research Summary Vitamin C in humans must be ingested for survival. As an electron donor, vitamin C acts as a potent water-soluble antioxidant. This property underlies all of its known functions. The antioxidant effects of vitamin C have been demonstrated in numerous in vitro experiments. Human diseases such as atherosclerosis and cancer might partially result from oxidant damage to tissues. Oxidation of lipids, proteins, and DNA leads to specific oxidation products that can be measured in laboratory settings. While these biomarkers of oxidation have been measured in humans, the assays used are neither validated nor standardized, and the connection between...

Research Summary One of the main functions of cutaneous tissues is to protect our body from outdoor insults. Ozone (O3) is among the most toxic stressors to which we are continuously exposed, and due to its critical location, the skin is one of the most susceptible tissues to the oxidative damaging effects of O3. While O3 is not able to penetrate the skin, and is not a radical per se, the damage is mainly a result of its ability to induce oxidative stress via the formation of lipid peroxidation products.Aim of StudyIn this study, we investigated the protective effect of...

Research Summary Sun protection products have been used to mitigate the harmful effects of Ultra Violet (UV) sun rays for centuries. These products protect against sunlight-induced erythema, with their level of performance indicated by the sun protection factor (SPF). The present investigation was conducted with the aim of determining the effect of different concentrations of titanium dioxide on SPF using mice as test subjects.In this study, the mice were divided into four groups. Group I served as the control, while Groups II and III served as test groups, treated with formulations containing 10% and 20% titanium dioxide, respectively. All the...

Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which leads to dermatitis, diarrhea, dementia, and possibly death, depending on its severity and duration. Vitamin B3 is used in the synthesis of the NAD+ family of coenzymes, contributing to cellular energy metabolism and defense systems. Although nicotinamide (niacinamide) is primarily used as a nutritional supplement for vitamin B3, its pharmaceutical and cosmeceutical uses have been extensively explored.In this review, we discuss the biological activities and cosmeceutical properties of nicotinamide in consideration of its metabolic pathways. Supplementation of nicotinamide restores the cellular NAD+ pool and mitochondrial energetics, attenuates oxidative...