nouvelles-1 — Ingredients

Research Summary: Although many cosmeceutical formulations contain vitamin C and/or vitamin E, very few are actually effective in topical application. This is due to several factors. First, the concentration of these vitamins is often too low. Second, their stability is compromised once the product is opened and exposed to air and light. Third, the form of the molecule (either an ester or a mixture of isomers) may not be effectively absorbed or metabolized by the skin.However, when a stable formulation delivers a high concentration of the nonesterified, optimal isomer of the antioxidant, vitamins C and E can indeed inhibit the...

Research Summary: The purpose of this randomized, placebo-controlled, blind study was to investigate the effects of the drinkable nutraceutical ELASTEN® (QUIRIS Healthcare, Gütersloh, Germany) on skin aging and skin health. The drinkable ampoules provide a blend of 2.5 g of collagen peptides, acerola fruit extract, vitamin C, zinc, biotin, and a native vitamin E complex. This controlled interventional trial was conducted with 72 healthy women aged 35 years or older. Participants received either the food supplement (n = 36) or a placebo (n = 36) for twelve weeks. A skin assessment was performed based on objective validated methods, including corneometry...

Research Summary: It has been recognized that the vehicle in which a permeant is applied to the skin has a distinctive effect on the dermal and transdermal delivery of active ingredients. The cutaneous and percutaneous absorptions can be enhanced, for example, by an increase in thermodynamic activity, supersaturation, and penetration modifiers. Furthermore, dermal and transdermal delivery can be influenced by the interactions that may occur between the vehicle and the skin on the one hand, and interactions between the active ingredient and the skin on the other hand.Emulsions are widely used as cosmetic and pharmaceutical formulations because of their excellent...

Research Summary: Glycerol is a trihydroxy alcohol that has been included for many years in topical dermatological preparations. In addition, endogenous glycerol plays a role in skin hydration, cutaneous elasticity, and epidermal barrier repair. The aquaporin-3 transport channel and lipid metabolism in the pilosebaceous unit have been evidenced as potential pathways for endogenous delivery of glycerol and for its metabolism in the skin. Multiple effects of glycerol on the skin have been reported. The diverse actions of the polyol glycerol on the epidermis include improvement of stratum corneum hydration, skin barrier function, and skin mechanical properties. It also inhibits the...