Research

Research Summary The last two decades have seen a rise in active-led skincare products in the over-the-counter and retail markets. Consumers have become increasingly knowledgeable about ingredients used in topical products, resulting in formulations with vitamins and other active ingredients gaining popularity. Additionally, with the growing demand for instant and short-term benefits, consumers are gravitating toward high doses of active products. This trend poses a challenge for formulation scientists, who must stabilize these high active doses and ensure potency over the product's shelf life.Vitamin C, or ascorbic acid, is one such ubiquitous active ingredient commonly found in topical products that...

Research Summary Background: Moisturizers are foundational therapies for treating human atopic dermatitis. In veterinary medicine, the use of moisturizers has been recommended by an expert committee to alleviate skin dryness that occurs, for example, in canine atopic dermatitis (cAD). However, little is known about the effects of moisturizers on the skin barrier in veterinary patients.Hypothesis/Objectives: This study aimed to investigate the effects of a moisturizer on skin barrier recovery in a canine model of chronic mechanical barrier disruption.Animals: The study involved six healthy beagle dogs maintained in a laboratory setting.Methods and Materials: A model of chronic skin barrier disruption was...

Research Summary Green, porous, and eco-friendly scaffolds have been recognized as potent candidates for tissue engineering substitutes. This study aims to investigate the biocompatibility of hydroxyethyl cellulose (HEC) and silver nanoparticles (AgNPs), prepared using the green synthesis method, as a potential host material for skin tissue applications. The substrates, containing varied concentrations of AgNO3 (0.4%–1.6%), were formed in the presence of HEC and dissolved in a single step in water. The presence of AgNPs was visually confirmed by a color change from colorless to dark brown and fabricated via the freeze-drying technique.The results exhibited significant porosity (above 80%), a moderate...

Research Summary Skin serves as the first business card in human social life. Its structure, texture, and color convey our health and wellness status. Unfortunately, the appearance of wrinkles and sagginess is a natural phenomenon of aging, which can impact one's psychological well-being. As lifespans increase and there is a growing emphasis on improving lifestyle, more individuals are seeking solutions for the signs of aging.Cosmetics play a scientific role in discovering molecules that help maintain the health of the skin. The purpose of this review is to explore the origins of wrinkles and the treatments that cosmetology and aesthetic medicine...