Research — aging

Research Summary: Niacinamide, also known as vitamin B3, is an essential nutrient that, once inside the body, is converted into the co-factors NADH and NADPH. These co-factors are involved in numerous biochemical reactions. A deficiency of this water-soluble vitamin, a member of the vitamin B family, causes pellagra, a disease characterized by dermatitis and red lesions. Pellagra led to thousands of deaths in the United States during the first half of the 20th century until dietary supplementation with niacinamide was found to cure the condition.As we age, NAD+ and NADPH levels in skin cells decline. Therefore, supplementing the skin with...

Research Summary: The sun-and-skin interactions have controversial sides. Besides important beneficial effects, we also need to take into consideration some serious harmful results. In particular, these are connected to the portion of the solar spectrum traditionally identified as ultraviolet type A and B. The topical application of sunscreens (and the avoidance of extreme exposure to sun rays) is worldwide recognized as the best strategy to avoid sunburn and edema. Moreover, such a strategy can efficiently prevent the onset of skin cancer.Therefore, the first aim of sunscreen products is to efficiently minimize all damage from sun exposure, while, at the same...

Research Summary: The purpose of this randomized, placebo-controlled, blind study was to investigate the effects of the drinkable nutraceutical ELASTEN® (QUIRIS Healthcare, Gütersloh, Germany) on skin aging and skin health. The drinkable ampoules provide a blend of 2.5 g of collagen peptides, acerola fruit extract, vitamin C, zinc, biotin, and a native vitamin E complex. This controlled interventional trial was conducted with 72 healthy women aged 35 years or older. Participants received either the food supplement (n = 36) or a placebo (n = 36) for twelve weeks. A skin assessment was performed based on objective validated methods, including corneometry...

Research Summary:Background: Nutritional factors play a key role in normal dermatologic functioning. However, little is known about the effects of diet on skin-aging appearance.Objective: We evaluated the associations between nutrient intakes and skin-aging appearance.Design: Using data from the first National Health and Nutrition Examination Survey, we examined associations between nutrient intakes and skin aging in 4025 women aged 40 to 74 years. Nutrients were estimated from a 24-hour recall. Clinical examinations of the skin were conducted by dermatologists. Skin-aging appearance was defined as having a wrinkled appearance, senile dryness, and skin atrophy.Results: Higher vitamin C intakes were associated with a...