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Anti-Aging Effects of Low Molecular Weight Collagen Peptides Supplementation on Facial Wrinkles and Skin Hydration: Outcomes from a  Six-Week Randomized, Double-Blind, Placebo- Controlled Trial

Anti-Aging Effects of Low Molecular Weight Collagen Peptides Supplementation on Facial Wrinkles and Skin Hydration: Outcomes from a Six-Week Randomized, Double-Blind, Placebo- Controlled Trial

Research Summary: In recent decades, there has been a rising demand for anti-aging interventions aimed at postponing or potentially reversing indicators of skin aging. The use of collagen-based nutraceutical supplements has gained popularity as they have shown promise in enhancing skin health and reducing signs of aging. The aim of this randomized, placebo-controlled, blinded study was to investigate the effects of 2.5 g COLLinstant® LMW, a novel cosmeceutical containing low molecular weight (≤ 1000 Da) collagen peptides, on skin aging and health. The trial was conducted in 80 healthy women aged 30 years and older. They received a daily oral...

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Common skin disorders in the elderly

Common skin disorders in the elderly

Research Summary: Ageing causes a decline in the function of human skin, while factors such as medical conditions, drugs, and environmental irritants add to the compromised skin and predispose it to certain conditions. Superimposed on the changes of physiological ageing are changes characterized by chronic sun exposure. Skin neoplasia, whether benign, premalignant, or malignant, is more common in the elderly. It is important to identify benign conditions, as it is crucial that lesions with malignant potential be recognized so that timely treatment can prevent serious malignancies. Ultraviolet radiation is the major etiologic factor for the development of skin cancer.Pruritic conditions...

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Artocarpus heterophyllus leaves extract improve facial skin in clay mask formulation

Artocarpus heterophyllus leaves extract improve facial skin in clay mask formulation

Research Summary:Artocarpus heterophyllus (A. heterophyllus) is one of the plants commonly used for skin care. This study aimed to formulate a clay mask preparation with the active ingredient  A. heterophyllus 3% leaf extract and evaluate its activities in repairing facial moisture, smoothness, large pores, blemishes, and wrinkles. The process of preparing the clay masks began with the extraction of Artocarpus heterophyllus leaf ethanol extracts, ensuring standardized quality. This was followed by the preparation of clay mask bases with guaranteed quality, mixing the clay mask bases with the extracts, and testing the quality, stability, and effectiveness of the skin care product....

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Hydroxyethylcellulose as a versatile viscosity modifier in the development of liquid formulations

Hydroxyethylcellulose as a versatile viscosity modifier in the development of liquid formulations

Research Summary: Pharmaceutical formulations in liquid form for oral administration are commonly utilized for geriatric and pediatric patients who have difficulty swallowing solid dosage forms. Rheology, texture, and stability are among the Critical Quality Attributes (CQAs) that must be addressed in the development of oral liquid dosage forms. The distribution of pharmaceutical components relies on the manipulation of rheological properties and stabilization within these forms. The utilization of thickening agents to increase the viscosity of the liquid vehicle serves to reduce particle settling. Historically, sugars such as sucrose were used for this purpose, as well as for masking the taste...

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