Research Summary: Skin aging goes beyond a chronological process and also results from extrinsic factors referred to as the exposome. Hyaluronic acid (HA) is an important component of the extracellular matrix, with loss starting at the age of 25. While many studies of HA focus on its topical use, few literature reviews solely address the use of topical HA in dermatology. This review describes the various characteristics of HA-containing cosmeceuticals, with a focus on skin aging and the impact of exposome factors on HA synthesis and degradation.A review was conducted using terms such as HA, hyaluronan, topical, dermatology, cosmetic, aging...
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