nouvelles-1

Research Summary New methods to protect the skin from photodamage caused by sun exposure are essential if we are to combat skin cancer and photoaging. While sunscreens are helpful, their protection is not ideal due to inadequate use, incomplete spectral coverage, and concerns about toxicity. The skin naturally employs antioxidants (AOs) to defend itself against photodamage. This scientific review summarizes current knowledge about how photodamage occurs, why sunscreens—the current gold standard for photoprotection—are insufficient, and how topical antioxidants can help protect against skin cancer and photoaging.This review serves as a reference source, including comprehensive reviews when available. Although not all...

Research Summary The skin is constantly exposed to various environmental stresses, particularly damage caused by pollution and ultraviolet (UV) radiation. As a result, the outermost layer, or horny extract, can be negatively affected by harmful surface components. The degradation processes initiated by UV radiation occur through several mechanisms. These include the direct absorption of radiation via cellular chromophores, which leads to the formation of excited states and subsequent chemical reactions, or photosensitization mechanisms. In photosensitization, UV light is absorbed by sensitizers, which become excited, triggering reactions that promote the formation of reactive oxygen species (ROS).The mechanisms through which polluting agents...

Research Summary Idebenone is an antioxidant and a lower molecular weight analogue of coenzyme Q10. Previous research has shown idebenone to be a highly effective antioxidant, protecting against cell damage from oxidative stress across various biochemical, cellular, and in vivo methods, including its ability to suppress sunburn cell (SBC) formation in living skin. However, no clinical studies had been conducted to establish the efficacy of idebenone in a topical skincare formulation for treating photodamaged skin prior to this study.In this non-vehicle control study, 0.5% and 1.0% idebenone commercial formulations were evaluated in a clinical trial for topical safety and efficacy...

Research Summary The use of clays in beauty care dates back to ancient times, with therapeutic applications since prehistory, and remains significantly relevant in today's global cosmetic industry. In this review, we describe the various types of clay and clay minerals used in cosmetics and dermocosmetics, including their compositions, uses as active compounds, cosmetic ingredients, and starting materials. We also provide observations about formulation techniques.From our review, we observed that while a substantial amount of scientific and specialized literature exists on the characterization of clays, only a few studies have included efficacy tests, particularly when clays are incorporated into cosmetic...