Contribution of Topical Antioxidants to Maintain Healthy Skin—A Review

Contribution of Topical Antioxidants to Maintain Healthy Skin—A Review

Research Summary

The skin is constantly exposed to various environmental stresses, particularly damage caused by pollution and ultraviolet (UV) radiation. As a result, the outermost layer, or horny extract, can be negatively affected by harmful surface components. The degradation processes initiated by UV radiation occur through several mechanisms. These include the direct absorption of radiation via cellular chromophores, which leads to the formation of excited states and subsequent chemical reactions, or photosensitization mechanisms. In photosensitization, UV light is absorbed by sensitizers, which become excited, triggering reactions that promote the formation of reactive oxygen species (ROS).

The mechanisms through which polluting agents impact the skin are not yet fully understood. However, evidence suggests that oxidative stress, specifically through lipid peroxidation, is one of the primary processes involved. This oxidative stress can damage sebum composition, impair the quality of the stratum corneum, and promote skin aging. Recent studies highlight the potential benefits of antioxidant agents, particularly those derived from natural sources, which aim to maintain the skin’s physiological balance.

Keywords: antioxidant, permeation, pollution, solar radiation, skin

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