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Research Summary: Lycium barbarum (Gouqizi, Fructus Lycii, Wolfberry) is well known for nourishing the liver, and in turn, improving eyesight. However, many people have forgotten its anti-aging properties. Valuable components of *L. barbarum* are not limited to its colored components containing zeaxanthin and carotene but include polysaccharides and small molecules such as betaine, cerebroside, β-sitosterol, p-coumaric acid, and various vitamins. Despite the fact that L. barbarum has been used for centuries, its beneficial effects on our bodies have not been comprehensively studied using modern technology to unravel its therapeutic effects at the biochemical level. Recently, our laboratory has demonstrated its...

Research Summary: Background: Skin aging manifests in various forms such as wrinkles, uneven skin tone, and dryness. Both intrinsic and extrinsic factors, especially ultraviolet light-induced oxidative radicals, contribute to the etiology of aging. Human skin requires both water- and lipid-soluble nutrient components, including hydrophilic and lipophilic antioxidants. Vitamins C and E play important protective roles in the aging process and must be supplied exogenously. Raspberry leaf extracts contain botanical actives with the potential to hydrate and moisturize the skin. Topical products containing these ingredients may therefore provide enhanced anti-aging effects compared to single-ingredient formulations.Objectives: This study aimed to evaluate the...

Research Summary:Skin aging has become a recurring concern even for younger people, primarily due to increased life expectancy. In this context, the use of nutricosmetics as supplements has gained popularity in recent years. Numerous scientific studies have demonstrated the benefits of hydrolyzed collagen supplementation in improving the signs of skin aging. The objective of this study was to summarize the evidence on the effects of hydrolyzed collagen supplementation on human skin through a systematic review followed by a meta-analysis of clinical trials, focusing on the process of skin aging.A literature search was conducted in the Medline, Embase, Cochrane, LILACS (Latin...

Research Summary:Background: Vitamin C is a micronutrient present in high concentrations in normal skin and is a highly prescribed cosmeceutical known for its protective effects against ultraviolet-induced pigmentation and its role in regulating collagen production. However, there is a lack of studies evaluating the efficacy of topical vitamin C in photoaging and melasma, making this systematic review the first to assess the existing evidence.Aim: This systematic review aims to evaluate whether topical vitamin C could be effective in reversing signs of photoaging and treating melasma.Methods: Prospective, randomized controlled trials that assessed protocols involving topically applied vitamin C in patients with...