Human skin is exposed daily to various environmental factors, including air pollutants and ultraviolet (UV) light. Air pollution is recognized as a significant environmental risk to human skin, promoting aging and inflammation that lead to skin disorders, wrinkles, and pigmentation issues. Moreover, components of air pollution can synergize with UV light, amplifying skin damage. Despite this, the role of air pollution in modulating cellular senescence in skin cells and its contribution to skin aging remains poorly understood. This review summarizes the current knowledge on air pollution components, their role in cellular senescence and skin aging, and the therapeutic and cosmetic...
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The increase in air pollution over the years has significantly impacted human skin. The skin is exposed to ultraviolet radiation (UVR) and environmental air pollutants such as polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds (VOCs), oxides, particulate matter (PM), ozone (O₃), and cigarette smoke. Although human skin functions as a biological shield against pro-oxidative chemical and physical air pollutants, prolonged or repetitive exposure to high levels of these pollutants can have profound negative effects. Such exposure has been linked to skin aging, as well as inflammatory and allergic skin conditions, including atopic dermatitis, eczema, psoriasis, and acne. Among the most...
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Research Summary: The skin is constantly exposed to various environmental stresses, particularly the damage caused by pollution and ultraviolet (UV) radiation. As a consequence, the outer layer of the skin can be negatively impacted by the harmful influence of some of its surface components. The mechanisms involved in the degradation processes promoted by UV radiation are driven by the direct absorption of radiation via cellular chromophores, the formation of excited states, and the consequent chemical reactions. In addition, photosensitization mechanisms occur, in which UV light is absorbed by sensitizers that become excited, leading to the formation of reactive oxygen species...
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The interactions between the sun and the skin have both beneficial and harmful aspects. While the sun provides important positive effects, there are also serious harmful consequences to consider, particularly from ultraviolet radiation, commonly referred to as UV-A and UV-B. To mitigate these harmful effects, the topical application of sunscreens and the avoidance of extreme sun exposure are widely recognized as the most effective strategies to prevent sunburn and skin edema. Additionally, this approach can efficiently reduce the risk of developing skin cancer.The primary aim of sunscreen products is to minimize the damage caused by sun exposure while maintaining good...
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