nouvelles-1 — skin concerns

Research Summary: The skin, being the largest organ in the human body, plays a pivotal role in safeguarding the body against invasive pathogens. Therefore, it is essential to reinforce and protect this vital organ. Current research supports the impact of probiotics on skin health and their ability to alleviate various skin disorders. However, the effectiveness and potential side effects of probiotics in skincare remain a subject of debate, necessitating further investigation and analysis. This study aims to highlight existing gaps and future needs in the current research on probiotics in skincare, paving the way for future investigations.We examined the effects...

Research Summary: Stem cells are precursor cells present in many tissues with the ability to differentiate into various types of cells. This interesting property of plasticity can have therapeutic implications, and there has been substantial research in this field over the last few decades. As a result, stem cell therapy is now used as a therapeutic modality in many conditions, and it has made its way into dermatology as well. Stem cells can be classified based on their source and differentiating capacity. In the skin, they are present in the inter-follicular epidermis, hair follicle, dermis, and adipose tissue, helping to...

Research Summary: It is estimated that total sun exposure occurs non-intentionally in three quarters of our lifetimes. Our skin is exposed to the majority of UV radiation during outdoor activities, such as walking, practicing sports, running, hiking, etc., and not when we are intentionally exposed to the sun on the beach. We rarely use sunscreens during those activities, or at least not as much and as regularly as we should, making us commonly prone to acute and chronic sun damage of the skin. The only protection of our skin is endogenous (synthesis of melanin and enzymatic antioxidants) and exogenous (antioxidants,...

Research Summary: Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to be less immunogenic, or perhaps even non-immunogenic, with a variety of physicochemical properties, there is mounting evidence that PEG causes immunogenic responses when conjugated with other materials such as proteins and nanocarriers. Under these conditions, PEG with other materials can result in the production of anti-PEG antibodies after administration.The antibodies that are induced seem to have a deleterious impact on the therapeutic efficacy of subsequently administered PEGylated...