Research Summary: In modern society, people prefer to look well-groomed and presentable. Although this is completely based on individual taste and personality, beauty products greatly help in enhancing external appearance. There are many natural and synthetic cosmetic ingredients in beauty products that provide an aesthetic effect to the individual. As society and science advance, the search for newer cosmetic ingredients continues, offering renewed hope to the growing beauty industry and consumers. Conditioned media has emerged as one of the disruptive innovations of recent times in cosmetic ingredients, providing superior products compared to conventional options. New-generation cosmetic products containing growth factors...
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Research Summary: Skin reflects origin, lifestyle, age, and state of health. Skin color, tone and evenness, pigmentation, as well as skin surface characteristics, are signs of skin health. The cosmetic and pharmaceutical industries offer a vast armamentarium of skin care products and procedures to clean, soothe, restore, reinforce, protect, and treat our skin, helping to keep it in good condition. Skin care products are readily available in daily life and play a major role in health and nursing care.The promotion of skin care products, including their claims, is often based on an effect (e.g., moisturizing, antioxidant), evoked by an active...
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Research Summary: It is estimated that total sun exposure occurs non-intentionally in three quarters of our lifetimes. Our skin is exposed to the majority of UV radiation during outdoor activities, such as walking, practicing sports, running, hiking, etc., and not when we are intentionally exposed to the sun on the beach. We rarely use sunscreens during those activities, or at least not as much and as regularly as we should, making us commonly prone to acute and chronic sun damage of the skin. The only protection of our skin is endogenous (synthesis of melanin and enzymatic antioxidants) and exogenous (antioxidants,...
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Research Summary: Retinoic acid (RA) is the biologically active metabolite of vitamin A. It is a low molecular weight, lipophilic molecule that acts on the nucleus to induce gene transcription. In amphibians and mammals, it induces the regeneration of several tissues and organs, and these examples are reviewed here. RA induces the "super-regeneration" of organs that can already regenerate, such as the urodele amphibian limb, by respecifying positional information in the limb. In organs that cannot normally regenerate, such as the adult mammalian lung, RA induces the complete regeneration of alveoli that have been destroyed by various noxious treatments. In...
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