Research Summary Sun protection products have been used to mitigate the harmful effects of Ultra Violet (UV) sun rays for centuries. These products protect against sunlight-induced erythema, with their level of performance indicated by the sun protection factor (SPF). The present investigation was conducted with the aim of determining the effect of different concentrations of titanium dioxide on SPF using mice as test subjects.In this study, the mice were divided into four groups. Group I served as the control, while Groups II and III served as test groups, treated with formulations containing 10% and 20% titanium dioxide, respectively. All the...
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Research Summary: Cyclic and linear siloxanes are compounds synthesized from silicon, consisting of alternating atoms of silicone and oxygen [Si-O] units with organic side chains. The most common cyclic siloxanes are octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and dodecamethylcyclohexasiloxane (D6), while the most common linear siloxanes are high molecular weight polydimethylsiloxanes (PDMS) and low molecular weight volatile linear siloxanes known as hexamethyldisiloxane (L2), octamethyltrisiloxane (L3), decamethyltetrasiloxane (L4), and dodecamethylpentasiloxane (L5). These compounds exhibit low dermal toxicity, are generally inert and non-reactive, and are compatible with a wide range of chemicals. They offer beneficial properties such as wash-off or transfer resistance from the...
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Research Summary: Ageing causes a decline in the function of human skin, while factors such as medical conditions, drugs, and environmental irritants add to the compromised skin and predispose it to certain conditions. Superimposed on the changes of physiological ageing are changes characterized by chronic sun exposure. Skin neoplasia, whether benign, premalignant, or malignant, is more common in the elderly. It is important to identify benign conditions, as it is crucial that lesions with malignant potential be recognized so that timely treatment can prevent serious malignancies. Ultraviolet radiation is the major etiologic factor for the development of skin cancer.Pruritic conditions...
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Research Summary: The following work describes the synthesis of new physical filters based on TiO2/SiO2 and TiO2/Ag nanostructures. Titanium dioxide nanoparticles (TiO2 NPs) were applied as control material and a popular physical UV filter. The advantage of using materials on the nanometer scale is the elimination of the skin whitening effect that occurs when using photoprotective cosmetics containing titanium dioxide on a macro scale. In addition, the silica coating makes the material less harmful, and the silver coating enriches the material with antibacterial properties.Nanoparticles and nanostructures have been characterized by Energy Dispersive X-Ray Analysis (EDX), the Scanning Electron Microscope (SEM),...
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