notizie-1 — microbiome

Molecular Cell Biology

Molecular Cell Biology

Research Summary: Proteins are fundamental to cell structure and function. They provide the necessary framework that gives cells their shape and are involved in nearly every task within a cell, from metabolism to DNA replication.Nucleic acids, such as DNA and RNA, store and convey the genetic instructions for the production of proteins. These molecules ensure that proteins are synthesized in the appropriate quantity, at the correct time, and within the right cellular location.Phospholipids form the basic structure of cell membranes. These lipid molecules arrange themselves in a bilayer, creating a barrier that regulates what enters and exits the cell, maintaining...

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A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora

A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora

Research Summary: Purpose: Two randomized, intra-individual comparison studies were performed in healthy subjects to evaluate the skin moisturization and barrier restoration potential of a new topical panthenol-containing emollient (NTP-CE) (Study 1) and its effect on skin microflora (Study 2).Methods: In Study 1 (N = 23), two skin areas, one challenged with 0.5% sodium dodecyl sulfate (SDS) solution and one unchallenged, were treated with NTP-CE for 3 weeks. Transepidermal water loss (TEWL), skin hydration, and intercellular lipid lamellae (ICLL) organization were measured at regular intervals during the study. In Study 2 (N = 20), quantitative bacterial cultures were obtained over 6...

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