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Research Summary: The skin, being the largest organ in the human body, plays a pivotal role in safeguarding the body against invasive pathogens. Therefore, it is essential to reinforce and protect this vital organ. Current research supports the impact of probiotics on skin health and their ability to alleviate various skin disorders. However, the effectiveness and potential side effects of probiotics in skincare remain a subject of debate, necessitating further investigation and analysis. This study aims to highlight existing gaps and future needs in the current research on probiotics in skincare, paving the way for future investigations.We examined the effects...

The interactions between the sun and the skin have both beneficial and harmful aspects. While the sun provides important positive effects, there are also serious harmful consequences to consider, particularly from ultraviolet radiation, commonly referred to as UV-A and UV-B. To mitigate these harmful effects, the topical application of sunscreens and the avoidance of extreme sun exposure are widely recognized as the most effective strategies to prevent sunburn and skin edema. Additionally, this approach can efficiently reduce the risk of developing skin cancer.The primary aim of sunscreen products is to minimize the damage caused by sun exposure while maintaining good...

Research Summary: This study investigated the effects of a skin protectant solution (dimethicone 2%) on clinical signs and skin barrier function in canine atopic dermatitis (AD). Eighteen dogs with AD were randomly divided into two groups, with one group receiving dimethicone and the other receiving the vehicle (cyclomethicone) on selected areas (pinnae, groin, and axillae) daily for 4 weeks. Owners and investigators were blinded to group allocation.Clinical efficacy was evaluated using a scoring system, and skin barrier function was assessed by measuring transepidermal water loss (TEWL). Twelve dogs completed the study, with a 50% drop rate in the vehicle group...

Research Summary: Stem cells are precursor cells present in many tissues with the ability to differentiate into various types of cells. This interesting property of plasticity can have therapeutic implications, and there has been substantial research in this field over the last few decades. As a result, stem cell therapy is now used as a therapeutic modality in many conditions, and it has made its way into dermatology as well. Stem cells can be classified based on their source and differentiating capacity. In the skin, they are present in the inter-follicular epidermis, hair follicle, dermis, and adipose tissue, helping to...