nouvelles-1 — vitamins

Research Summary: Researchers have identified vitamin E as essential to one’s diet and potentially beneficial for skincare. Vitamin E has been primarily reported to increase photoprotective properties and reduce erythema. However, some studies on scar formation and other effects have been inconclusive. More research under randomized controlled settings should be pursued to better understand the role vitamin E plays in skin health.Vitamin E's increasing photoprotective properties have been shown to benefit anti-aging and skin brightening. As it becomes more popular in cosmetics, the amount of vitamin E present in a product may not always be clear. To address this, scientists...

Research Summary Vitamin C in humans must be ingested for survival. As an electron donor, vitamin C acts as a potent water-soluble antioxidant. This property underlies all of its known functions. The antioxidant effects of vitamin C have been demonstrated in numerous in vitro experiments. Human diseases such as atherosclerosis and cancer might partially result from oxidant damage to tissues. Oxidation of lipids, proteins, and DNA leads to specific oxidation products that can be measured in laboratory settings. While these biomarkers of oxidation have been measured in humans, the assays used are neither validated nor standardized, and the connection between...

Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which leads to dermatitis, diarrhea, dementia, and possibly death, depending on its severity and duration. Vitamin B3 is used in the synthesis of the NAD+ family of coenzymes, contributing to cellular energy metabolism and defense systems. Although nicotinamide (niacinamide) is primarily used as a nutritional supplement for vitamin B3, its pharmaceutical and cosmeceutical uses have been extensively explored.In this review, we discuss the biological activities and cosmeceutical properties of nicotinamide in consideration of its metabolic pathways. Supplementation of nicotinamide restores the cellular NAD+ pool and mitochondrial energetics, attenuates oxidative...

Research Summary: Pharmaceutical formulations in liquid form for oral administration are commonly utilized for geriatric and pediatric patients who have difficulty swallowing solid dosage forms. Rheology, texture, and stability are among the Critical Quality Attributes (CQAs) that must be addressed in the development of oral liquid dosage forms. The distribution of pharmaceutical components relies on the manipulation of rheological properties and stabilization within these forms. The utilization of thickening agents to increase the viscosity of the liquid vehicle serves to reduce particle settling. Historically, sugars such as sucrose were used for this purpose, as well as for masking the taste...