nouvelles-1 — Moisturiser

Research Summary: Skin reflects origin, lifestyle, age, and state of health. Skin color, tone and evenness, pigmentation, as well as skin surface characteristics, are signs of skin health. The cosmetic and pharmaceutical industries offer a vast armamentarium of skin care products and procedures to clean, soothe, restore, reinforce, protect, and treat our skin, helping to keep it in good condition. Skin care products are readily available in daily life and play a major role in health and nursing care.The promotion of skin care products, including their claims, is often based on an effect (e.g., moisturizing, antioxidant), evoked by an active...

Research Summary: This study aims to evaluate the skin moisturizing efficacy of formulations containing different concentrations of panthenol. Formulations supplemented with or without 0.5%, 1.0%, or 5.0% panthenol were applied daily to the forearms of healthy subjects. Skin conditions in terms of moisture and transepidermal water loss (TEWL) were analyzed before and after 15- and 30-day periods of application. The formulations were also applied after skin washing with sodium laureth sulphate (SLES) to evaluate the immediate effects on TEWL and skin moisture. Panthenol-containing formulations (1.0% and 5.0%) produced significant decreases in TEWL after 30-day applications. In skin washed with SLES,...

Research Summary: Cyclic and linear siloxanes are compounds synthesized from silicon, consisting of alternating atoms of silicone and oxygen [Si-O] units with organic side chains. The most common cyclic siloxanes are octamethylcyclotetrasiloxane (D4), decamethylcyclopentasiloxane (D5), and dodecamethylcyclohexasiloxane (D6), while the most common linear siloxanes are high molecular weight polydimethylsiloxanes (PDMS) and low molecular weight volatile linear siloxanes known as hexamethyldisiloxane (L2), octamethyltrisiloxane (L3), decamethyltetrasiloxane (L4), and dodecamethylpentasiloxane (L5). These compounds exhibit low dermal toxicity, are generally inert and non-reactive, and are compatible with a wide range of chemicals. They offer beneficial properties such as wash-off or transfer resistance from the...

Research Summary: Purpose: Two randomized, intra-individual comparison studies were performed in healthy subjects to evaluate the skin moisturization and barrier restoration potential of a new topical panthenol-containing emollient (NTP-CE) (Study 1) and its effect on skin microflora (Study 2).Methods: In Study 1 (N = 23), two skin areas, one challenged with 0.5% sodium dodecyl sulfate (SDS) solution and one unchallenged, were treated with NTP-CE for 3 weeks. Transepidermal water loss (TEWL), skin hydration, and intercellular lipid lamellae (ICLL) organization were measured at regular intervals during the study. In Study 2 (N = 20), quantitative bacterial cultures were obtained over 6...