Research Summary:
We are honored to present to the readers the book entitled *Carrier-Mediated Dermal Delivery: Applications in the Prevention and Treatment of Skin Disorders*, which is based on the systematic revision of the most recent findings. This book contains several contributions on new approaches for the management of skin aging and photocarcinogenesis, as well as topical formulations based on nanocarrier systems for skin disorders. These chapters discuss the structure and skin morphology in detail. Cosmeceuticals, laser and photodynamic therapy, and melatonin-based treatments are presented as important strategies for photoaging management. Photodynamic therapy and melatonin can also be used in the context of photocarcinogenesis. Therefore, the inclusion of this strong antioxidant in sunscreen products could be a promising approach. The book discusses the safety and efficacy of sunscreen products as well.
Topical formulations, including emulsions (conventional formulations and emulsions stabilized by solid particles), nail films, and nanocarriers used for different active delivery, are reviewed in the context of certain skin and nail diseases (e.g., acne, psoriasis, atopic dermatitis, fungal diseases, leishmaniasis, and skin cancer). Finally, several nanocarriers are introduced, such as lipid vesicles (from the first generation of conventional liposomes to the more recent deformable vesicles), liquid crystalline nanodispersions, and gelatin and solid lipid nanoparticles. Their composition, formulation process, characterization, and examples of topical applications are discussed in detail for each system.
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