Research Summary
Aloe is a perennial succulent from the Liliaceae family, long recognized for its diverse uses in medicinal preparations, drug extraction, and flavoring liquors. The exact origin of Aloe is uncertain, but it is primarily cultivated in relatively warm and dry climates. Two major products are derived from the leaves: the yellow bitter juice consisting of aloin, and the gel rich in polysaccharides. The plant also contains vitamins, enzymes, anthraquinones/anthrones, chromones, and numerous other primary and secondary metabolites.
These compounds are widely used as active ingredients in laxatives, anti-obesity medicines, and as emollients or wound healers in various cosmetic and pharmaceutical formulations. Many tribal communities have developed their own indigenous Aloe-based remedies to manage various ailments for generations. However, despite Aloe's many beneficial properties, certain chemicals present in the plant can render its products toxic. This toxicity can depend on the source, locality, and individual using the product.
The present study offers an extensive review of the phytochemistry, multi-dimensional health benefits, and toxicological profile of Aloe species.
Keywords: Aloe sp, phytochemistry, pharmaceuticals, human health, toxicology.
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