Research Summary
Disruption of the skin barrier and immunity has been associated with several skin diseases, namely atopic dermatitis (AD), psoriasis, and acne. Resident and non-resident immune cells, along with the barrier system of the skin, are integral to innate immunity.
Recent advances in understanding skin microbiota have expanded the scope of research into the various communications between these microbiota and skin immune cells. Vitamins, being essential micronutrients, have been reported to exert antioxidant, anti-inflammatory, and anti-microbial effects. The immunomodulatory action of vitamins can halt the progression of skin diseases, making the study of their immuno-pharmacology critical for potential therapeutic applications.
At the same time, exploring the molecular and cellular markers modulated by these vitamins and their derivatives is necessary. This review focuses on significant vitamins (A, B3, C, D, and E), commonly consumed as nutritional supplements, to discuss the outcomes and the scope of studies related to skin immunity, health, and diseases.
Keywords: Skin diseases, Immunity, Vitamins, Microbiome.
<Access the full report below>