Research Summary:
The skin is constantly exposed to various environmental stresses, particularly the damage caused by pollution and ultraviolet (UV) radiation. As a consequence, the outer layer of the skin can be negatively impacted by the harmful influence of some of its surface components. The mechanisms involved in the degradation processes promoted by UV radiation are driven by the direct absorption of radiation via cellular chromophores, the formation of excited states, and the consequent chemical reactions. In addition, photosensitization mechanisms occur, in which UV light is absorbed by sensitizers that become excited, leading to the formation of reactive oxygen species (ROS).
The mechanisms of polluting agents are not yet fully understood. However, it has been indicated that one of the main mechanisms involved is oxidative stress, primarily through lipid peroxidation. This process has the ability to damage the composition of sebum, affect the quality of the stratum corneum, and ultimately promote skin aging.
Recent studies highlight the potential of antioxidant agents, particularly those derived from natural sources, which aim to promote the maintenance of the skin's physiological balance.
Keywords: antioxidant, permeation, pollution, solar radiation, skin.
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